OUR PIPELINE​

Our Pipeline Is Designed To Address Critical Unmet Needs

VRON-0200: Treatment of HBV Infection

The T Cell Platform for Multi-Modal Therapies & Functional Cure

VRON-0200 is designed to address a global high unmet medical need for chronic HBV infection. VRON-0200 combines a genetically encoded checkpoint modifier along with selected and optimized antigens of choice and delivered by ChiVax™, our heterologous chimpanzee adenoviral vectors that promotes potent, prolonged, and broad CD8+ T cell responses. Results from our Phase 1b clinical trial have shown durable anti-HBV activity, after a single VRON-0200 dose, in the majority of chronically HBV-infected participants.

Learn more about VRON-0200

Abbreviations and References

CD, cluster of differentiation; FDA, Food and Drug Administration; gCPM, genetically encoded checkpoint modifier; gD, glycoprotein D; HBV, hepatitis B virus; HIV, human immunodeficiency virus; HPV, human papillomavirus; IND, investigational new drug; MOA, mechanism of action; NIH, National Institutes of Health.

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